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Did you mean robert a baker[Author] (142 results)?
In Chagas disease, transforming growth factor beta neutralization reduces Trypanosoma cruzi infection and improves cardiac performance.
Ferreira RR, de Souza EM, Vilar-Pereira G, Degrave WMS, Abreu RDS, Meuser-Batista M, Ferreira NVC, Ledbeter S, Barker RH, Bailly S, Feige JJ, Lannes-Vieira J, de Araújo-Jorge TC, Waghabi MC. Ferreira RR, et al. Among authors: barker rh. Front Cell Infect Microbiol. 2022 Nov 30;12:1017040. doi: 10.3389/fcimb.2022.1017040. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 36530434 Free PMC article.
Brain Penetrable Inhibitors of Ceramide Galactosyltransferase for the Treatment of Lysosomal Storage Disorders.
Thurairatnam S, Lim S, Barker RH Jr, Choi-Sledeski YM, Hirth BH, Jiang J, Macor JE, Makino E, Maniar S, Musick K, Pribish JR, Munson M. Thurairatnam S, et al. Among authors: barker rh jr. ACS Med Chem Lett. 2020 Jun 16;11(10):2010-2016. doi: 10.1021/acsmedchemlett.0c00120. eCollection 2020 Oct 8. ACS Med Chem Lett. 2020. PMID: 33062186 Free PMC article.
Identification and validation of tetracyclic benzothiazepines as Plasmodium falciparum cytochrome bc1 inhibitors.
Dong CK, Urgaonkar S, Cortese JF, Gamo FJ, Garcia-Bustos JF, Lafuente MJ, Patel V, Ross L, Coleman BI, Derbyshire ER, Clish CB, Serrano AE, Cromwell M, Barker RH Jr, Dvorin JD, Duraisingh MT, Wirth DF, Clardy J, Mazitschek R. Dong CK, et al. Among authors: barker rh jr. Chem Biol. 2011 Dec 23;18(12):1602-10. doi: 10.1016/j.chembiol.2011.09.016. Chem Biol. 2011. PMID: 22195562 Free PMC article.
Diversity-Oriented Synthesis Yields a Novel Lead for the Treatment of Malaria.
Heidebrecht RW Jr, Mulrooney C, Austin CP, Barker RH Jr, Beaudoin JA, Cheng KC, Comer E, Dandapani S, Dick J, Duvall JR, Ekland EH, Fidock DA, Fitzgerald ME, Foley M, Guha R, Hinkson P, Kramer M, Lukens AK, Masi D, Marcaurelle LA, Su XZ, Thomas CJ, Weïwer M, Wiegand RC, Wirth D, Xia M, Yuan J, Zhao J, Palmer M, Munoz B, Schreiber S. Heidebrecht RW Jr, et al. Among authors: barker rh jr. ACS Med Chem Lett. 2012 Feb 9;3(2):112-117. doi: 10.1021/ml200244k. Epub 2011 Dec 22. ACS Med Chem Lett. 2012. PMID: 22328964 Free PMC article.
Novel S-adenosyl-L-methionine decarboxylase inhibitors as potent antiproliferative agents against intraerythrocytic Plasmodium falciparum parasites.
le Roux D, Burger PB, Niemand J, Grobler A, Urbán P, Fernàndez-Busquets X, Barker RH, Serrano AE, I Louw A, Birkholtz LM. le Roux D, et al. Among authors: barker rh. Int J Parasitol Drugs Drug Resist. 2013 Dec 5;4(1):28-36. doi: 10.1016/j.ijpddr.2013.11.003. eCollection 2014 Apr. Int J Parasitol Drugs Drug Resist. 2013. PMID: 24596666 Free PMC article.
Aminoindoles, a novel scaffold with potent activity against Plasmodium falciparum.
Barker RH Jr, Urgaonkar S, Mazitschek R, Celatka C, Skerlj R, Cortese JF, Tyndall E, Liu H, Cromwell M, Sidhu AB, Guerrero-Bravo JE, Crespo-Llado KN, Serrano AE, Lin JW, Janse CJ, Khan SM, Duraisingh M, Coleman BI, Angulo-Barturen I, Jiménez-Díaz MB, Magán N, Gomez V, Ferrer S, Martínez MS, Wittlin S, Papastogiannidis P, O'Shea T, Klinger JD, Bree M, Lee E, Levine M, Wiegand RC, Munoz B, Wirth DF, Clardy J, Bathurst I, Sybertz E. Barker RH Jr, et al. Antimicrob Agents Chemother. 2011 Jun;55(6):2612-22. doi: 10.1128/AAC.01714-10. Epub 2011 Mar 21. Antimicrob Agents Chemother. 2011. PMID: 21422215 Free PMC article.
Optimization of Potent Inhibitors of P. falciparum Dihydroorotate Dehydrogenase for the Treatment of Malaria.
Skerlj RT, Bastos CM, Booker ML, Kramer ML, Barker RH Jr, Celatka CA, O'Shea TJ, Munoz B, Sidhu AB, Cortese JF, Wittlin S, Papastogiannidis P, Angulo-Barturen I, Jimenez-Diaz MB, Sybertz E. Skerlj RT, et al. Among authors: barker rh jr. ACS Med Chem Lett. 2011 Jul 11;2(9):708-13. doi: 10.1021/ml200143c. eCollection 2011 Sep 8. ACS Med Chem Lett. 2011. PMID: 24900364 Free PMC article.
Cofactor-independent phosphoglycerate mutase from nematodes has limited druggability, as revealed by two high-throughput screens.
Crowther GJ, Booker ML, He M, Li T, Raverdy S, Novelli JF, He P, Dale NR, Fife AM, Barker RH Jr, Kramer ML, Van Voorhis WC, Carlow CK, Wang MW. Crowther GJ, et al. Among authors: barker rh jr. PLoS Negl Trop Dis. 2014 Jan 9;8(1):e2628. doi: 10.1371/journal.pntd.0002628. eCollection 2014. PLoS Negl Trop Dis. 2014. PMID: 24416464 Free PMC article.
17 results